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| the eukaryotic cell cycle and cancer: The Eukaryotic Cell Cycle J. A. Bryant, Dennis Francis, 2008 Written by respected researchers, this is an excellent account of the eukaryotic cell cycle that is suitable for graduate and postdoctoral researchers. It discusses important experiments, organisms of interest and research findings connected to the different stages of the cycle and the components involved. |
| the eukaryotic cell cycle and cancer: The Cell Cycle and Cancer Renato Baserga, 1971 |
| the eukaryotic cell cycle and cancer: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy. |
| the eukaryotic cell cycle and cancer: Principles of Biology Lisa Bartee, Walter Shiner, Catherine Creech, 2017 The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research. |
| the eukaryotic cell cycle and cancer: Molecular Biology of the Cell , 2002 |
| the eukaryotic cell cycle and cancer: Cell Cycle Regulation Philipp Kaldis, 2006-06-26 This book is a state-of-the-art summary of the latest achievements in cell cycle control research with an outlook on the effect of these findings on cancer research. The chapters are written by internationally leading experts in the field. They provide an updated view on how the cell cycle is regulated in vivo, and about the involvement of cell cycle regulators in cancer. |
| the eukaryotic cell cycle and cancer: The Cell Cycle David Owen Morgan, 2007 The Cell Cycle: Principles of Control provides an engaging insight into the process of cell division, bringing to the student a much-needed synthesis of a subject entering a period of unprecedented growth as an understanding of the molecular mechanisms underlying cell division are revealed. |
| the eukaryotic cell cycle and cancer: Mitosis/Cytokinesis Arthur Zimmerman, 2012-12-02 Mitosis/Cytokinesis provides a comprehensive discussion of the various aspects of mitosis and cytokinesis, as studied from different points of view by various authors. The book summarizes work at different levels of organization, including phenomenological, molecular, genetic, and structural levels. The book is divided into three sections that cover the premeiotic and premitotic events; mitotic mechanisms and approaches to the study of mitosis; and mechanisms of cytokinesis. The authors used a uniform style in presenting the concepts by including an overview of the field, a main theme, and a conclusion so that a broad range of biologists could understand the concepts. This volume also explores the potential developments in the study of mitosis and cytokinesis, providing a background and perspective into research on mitosis and cytokinesis that will be invaluable to scientists and advanced students in cell biology. The book is an excellent reference for students, lecturers, and research professionals in cell biology, molecular biology, developmental biology, genetics, biochemistry, and physiology. |
| the eukaryotic cell cycle and cancer: Biology for AP ® Courses Julianne Zedalis, John Eggebrecht, 2017-10-16 Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences. |
| the eukaryotic cell cycle and cancer: Systems Biology of Cancer Sam Thiagalingam, 2015-04-09 An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer. |
| the eukaryotic cell cycle and cancer: Progress in Cell Cycle Research Laurent Meijer, Armelle Jézéquel, Bernard Ducommun, 2012-12-06 The Progress in Cell Cycle Research series is dedicated to serve as a collection of reviews on various aspects of the cell division cycle, with special emphasis on less studied aspects. We hope this series will continue to be helpful to students, graduates and researchers interested in the cell cycle area and related fields. We hope that reading of these chapters will constitute a point of entry into specific aspects of this vast and fast moving field of research. As PCCR4 is being printed several other books on the cell cycle have appeared (ref. 1-3) which should complement our series. This fourth volume of PCCR starts with a review on RAS pathways and how they impinge on the cell cycle (chapter 1). In chapter 2, an overview is presented on the links between cell anchorage -cytoskeleton and cell cycle progression. A model of the Gl control in mammalian cells is provided in chapter 3. The role of histone acetylation and cell cycle contriol is described in chapter 4. Then follow a few reviews dedicated to specific cell cycle regulators: the 14-3-3 protein (chapter 5), the cdc7/Dbf4 protein kinase (chapter 6), the two products of the pI6/CDKN2A locus and their link with Rb and p53 (chapter 7), the Ph085 cyclin-dependent kinases in yeast (chapter 9), the cdc25 phophatase (chapter 10), RCCI and ran (chapter 13). The intriguing phosphorylation dependent prolyl-isomerization process and its function in cell cycle regulation are reviewed in chapter 8. |
| the eukaryotic cell cycle and cancer: Oxford Textbook of Cancer Biology Francesco Pezzella, Mahvash Tavassoli, David Kerr, 2019-05-02 The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading. |
| the eukaryotic cell cycle and cancer: The Plant Cell Cycle Dirk Inzé, 2011-06-27 In recent years, the study of the plant cell cycle has become of major interest, not only to scientists working on cell division sensu strictu , but also to scientists dealing with plant hormones, development and environmental effects on growth. The book The Plant Cell Cycle is a very timely contribution to this exploding field. Outstanding contributors reviewed, not only knowledge on the most important classes of cell cycle regulators, but also summarized the various processes in which cell cycle control plays a pivotal role. The central role of the cell cycle makes this book an absolute must for plant molecular biologists. |
| the eukaryotic cell cycle and cancer: Cell Biology by the Numbers Ron Milo, Rob Phillips, 2015-12-07 A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid |
| the eukaryotic cell cycle and cancer: Molecular and Cell Biology of Cancer Rita Fior, Rita Zilhão, 2019-06-27 This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg “Hallmarks of Cancer” are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book’s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease |
| the eukaryotic cell cycle and cancer: Medical Cell Biology Steven R. Goodman, 2007-11-26 Medical Cell Biology, Third Edition, focuses on the scientific aspects of cell biology important to medical students, dental students, veterinary students, and prehealth undergraduates. With its National Board-type questions, this book is specifically designed to prepare students for this exam. The book maintains a concise focus on eukaryotic cell biology as it relates to human and animal disease, all within a manageable 300-page format. This is accomplished by explaining general cell biology principles in the context of organ systems and disease. This updated version contains 60% new material and all new clinical cases. New topics include apoptosis and cell death from a neural perspective; signal transduction as it relates to normal and abnormal heart function; and cell cycle and cell division related to cancer biology. - 60% New Material! - New Topics include: - Apoptosis and cell dealth from a neural perspective - Signal transduction as it relates to normal and abnormal heart function - Cell cycle and cell division related to cancer biology - All new clinical cases - Serves as a prep guide to the National Medical Board Exam with sample board-style questions (using Exam Master(R) technology): www.exammaster.com - Focuses on eukaryotic cell biology as it related to human disease, thus making the subject more accessible to pre-med and pre-health students |
| the eukaryotic cell cycle and cancer: Telomeres and Telomerase in Cancer Keiko Hiyama, 2009-03-18 Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets. Recently, role of telomerase in “cancer stem cells” has become another attractive story. Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge. |
| the eukaryotic cell cycle and cancer: MRCOG Part One Alison Fiander, Baskaran Thilaganathan, 2016-10-13 A fully updated and illustrated handbook providing comprehensive coverage of all curriculum areas covered by the MRCOG Part 1 examination. |
| the eukaryotic cell cycle and cancer: How Tobacco Smoke Causes Disease United States. Public Health Service. Office of the Surgeon General, 2010 This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products. |
| the eukaryotic cell cycle and cancer: The Physics of Cancer Caterina A. M. La Porta, Stefano Zapperi, 2017-04-20 Recent years have witnessed an increasing number of theoretical and experimental contributions to cancer research from different fields of physics, from biomechanics and soft-condensed matter physics to the statistical mechanics of complex systems. Reviewing these contributions and providing a sophisticated overview of the topic, this is the first book devoted to the emerging interdisciplinary field of cancer physics. Systematically integrating approaches from physics and biology, it includes topics such as cancer initiation and progression, metastasis, angiogenesis, cancer stem cells, tumor immunology, cancer cell mechanics and migration. Biological hallmarks of cancer are presented in an intuitive yet comprehensive way, providing graduate-level students and researchers in physics with a thorough introduction to this important subject. The impact of the physical mechanisms of cancer are explained through analytical and computational models, making this an essential reference for cancer biologists interested in cutting-edge quantitative tools and approaches coming from physics. |
| the eukaryotic cell cycle and cancer: Disease Pathways Anastasia P. Nesterova, Anton Yuryev, Eugene A. Klimov, Maria Zharkova, Maria Shkrob, Natalia V. Ivanikova, Sergey Sozin, Vladimir Sobolev, 2019-10-18 Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease. - Over 145 full-color illustrations of the molecular and cellular cascades underlying the disease pathology. - Disease pathways are based on computational models from Elsevier's Disease Pathway Collection, published for the first time outside of Pathway Studio® commercial software. - Each relationship on the pathway models is supported by references to scientific articles and can be examined at freely available online resources. |
| the eukaryotic cell cycle and cancer: Progress in Cell Cycle Research S. Guidet, S.V. Meijerink, H.Y.L. Tung, 2012-12-06 Progress in Cell Cycle Research is a new annual series designed to be the source for up-to-date research on this rapidly expanding field. Review articles by international experts examine various aspects of cell division regulation from fundamental perspectives to potential medical applications. Researchers as well as advanced undergraduate and graduate students in cell biology, biochemistry, and molecular biology will benefit from this series. |
| the eukaryotic cell cycle and cancer: Cancer Genomics for the Clinician Ramaswamy Govindan, MD, Siddhartha Devarakonda, MD, 2019-01-28 Cancer Genomics for the Clinician is a practical guide to cancer genomics and its application to cancer diagnosis and care. The book begins with a brief overview of the various types of genetic alterations that are encountered in cancer, followed by accessible and applicable information on next generation sequencing technology and bioinformatics; tumor heterogeneity; whole genome, exome, and transcriptome sequencing; epigenomics; and data analysis and interpretation. Each chapter provides essential explanations of concepts, terminology, and methods. Also included are tips for interpreting and analyzing molecular data, as well as a discussion of molecular predictors for targeted therapies covering hematologic malignancies and solid tumors. The final chapter explains the use of FDA-approved genomic-based targeted therapies for breast cancer, lung cancer, sarcomas, gastrointestinal cancers, urologic cancers, head and neck cancer, thyroid cancer, and many more. Assembled in an accessible format specifically designed for the non-expert, this book provides the clinical oncologist, early career practitioner, and trainee with an essential understanding of the molecular and genetic basis of cancer and the clinical aspects that have led to advancements in diagnosis and treatment. With this resource, physicians and trainees will increase their breadth of knowledge and be better equipped to educate patients and families who want to know more about their genetic predispositions to cancer and the targeted therapies that could be considered and prescribed. Key Features: Describes how cancer genomics and next generation sequencing informs cancer screening, risk factors, therapeutic options, and clinical management across cancer types Explains what mutations are, what tests are needed, and how to interpret the results Provides information on FDA-approved targeted therapies that are being used in the clinic Covers different sequencing platforms and technologies and how they perform in research settings Includes access to the fully searchable eBook |
| the eukaryotic cell cycle and cancer: Microbiology Nina Parker, OpenStax, Mark Schneegurt, AnhHue Thi Tu, Brian M. Forster, Philip Lister, 2016-05-30 Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology's art program enhances students' understanding of concepts through clear and effective illustrations, diagrams, and photographs. Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.--BC Campus website. |
| the eukaryotic cell cycle and cancer: Pancreatic Cancer Douglas B. Evans, Peter W.T. Pisters, James L. Abruzzese, 2002 The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons. |
| the eukaryotic cell cycle and cancer: The Biology of the Cell Cycle J. M. Mitchison, 1971-11-30 |
| the eukaryotic cell cycle and cancer: Molecular Cell Biology Harvey F. Lodish, 2008 The sixth edition provides an authoritative and comprehensive vision of molecular biology today. It presents developments in cell birth, lineage and death, expanded coverage of signaling systems and of metabolism and movement of lipids. |
| the eukaryotic cell cycle and cancer: Epigenetics and Dermatology Qianjin Lu, Christopher Chang, Bruce C. Richardson, 2015-02-16 Epigenetics and Dermatology explores the role of epigenetics in the pathogenesis of autoimmune-related skin diseases and skin cancer. Leading contributors cover common and uncommon skin conditions in which extensive epigenetic research has been done. They explain how environmental exposures (chemicals, drugs, sunlight, diet, stress, smoking, infection, etc.) in all stages of life (from a fetus in-utero to an elderly person) may result in epigenetic changes that lead to development of some skin diseases in life. They also discuss the possibilities of new and emergent epigenetic treatments which are gradually being adopted in management of various skin diseases. Chapters follow a conventional structure, covering fundamental biology of the disease condition, etiology and pathogenesis, diagnosis, commonly available treatments, and epigenetic therapy where applicable. Discusses the basic biology of skin diseases and skin cancers induced or aggravated by aberrant epigenetic changes Evaluates how to approach autoimmune-related skin diseases from a therapeutic perspective using the wealth of emergent epigenetic clinical trials Offers a coherent and structured table of contents with basic epigenetic biology followed by discussion of the spectrum of rheumatologic through neoplastic skin diseases, finally ending with a discourse on epigenetic therapy |
| the eukaryotic cell cycle and cancer: Telomeres and Telomerase Predrag Slijepcevic, 2008 Telomeres are essential functional elements of eukaryotic chromosomes. Their fundamental biological role as protectors of chromosome stability was identified for the first time in the 1930s by Hermann Muller and Barbara McClintock based on pioneering cytological experiments. Modern molecular research carried out more recently revealed that telomeres and telomerase play important roles in processes such as carcinogenesis and cellular senescence. This special issue presents the most recent developments in this highly active field of research. It is becoming increasingly clear that molecular pathways involved in regulation of telomere length and structure are functionally linked with pathways involved in DNA damage response, cellular stress response, chromatin organization and perhaps even pathways that regulate evolutionary chromosome rearrangements. The above functional link is explored by the leading experts in the field of telomere biology. Cell biologists, molecular biologists, oncologists, gerontologists, and radiobiologists with an interest in the role of telomeres/telomerase will appreciate the up-to-date information in this publication. |
| the eukaryotic cell cycle and cancer: Patterning and Cell Type Specification in the Developing CNS and PNS , 2013-05-06 The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. - Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop - Features leading experts in various subfields as Section Editors and article Authors - All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship - Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells |
| the eukaryotic cell cycle and cancer: The Physiology of Microalgae Michael A. Borowitzka, John Beardall, John A. Raven, 2016-03-21 This book covers the state-of-the-art of microalgae physiology and biochemistry (and the several –omics). It serves as a key reference work for those working with microalgae, whether in the lab, the field, or for commercial applications. It is aimed at new entrants into the field (i.e. PhD students) as well as experienced practitioners. It has been over 40 years since the publication of a book on algal physiology. Apart from reviews and chapters no other comprehensive book on this topic has been published. Research on microalgae has expanded enormously since then, as has the commercial exploitation of microalgae. This volume thoroughly deals with the most critical physiological and biochemical processes governing algal growth and production. |
| the eukaryotic cell cycle and cancer: Microbiome and Cancer Erle S. Robertson, 2019-02-20 This book ventures into a new and exciting area of discovery that directly ties our current knowledge of cancer to the discovery of microorganisms associated with different types of cancers. Recent studies demonstrate that microorganisms are directly linked to the establishment of cancers and that they can also contribute to the initiation, as well as persistence of, the cancers. Microbiome and Cancer covers the current knowledge of microbiome and its association with human cancers. It provides important reading for novices, senior undergraduates in cancer and microbiology, graduate students, junior investigators, residents, fellows and established investigators in the fields of cancer and microbiology. We cover areas related to known, broad concepts in microbiology and how they can relate to the ongoing discoveries of the micro-environment and the changes in the metabolic and physiologic states in that micro-environment, which are important for the ongoing nurturing and survival of the poly-microbial content that dictates activities in that micro-environment. We cover the interactions of microorganisms associated with gastric carcinomas, which are important for driving this particular cancer. Additional areas include oral cancers, skin cancers, ovarian cancers, breast cancers, nasopharyngeal cancers, lung cancers, mesotheliomas, Hodgkin’s and non-Hodgkin’s lymphomas, glioblastoma multiforme, hepatocellular carcinomas, as well as the inflammatory response related to the infectious agents in cancers. This book covers the metabolic changes that occur because of infection and their support for development of cancers, chronic infection and development of therapeutic strategies for detection and control of the infection. The field of microbiome research has exploded over the last five years, and we are now understanding more and more about the context in which microorganisms can contribute to the onset of cancers in humans. The field of microbiome research has demonstrated that the human body has specific biomes for tissues and that changes in these biomes at the specific organ sites can result in disease. These changes can result in dramatic differences in metabolic shifts that, together with genetic mutations, will produce the perfect niche for establishment of the particular infection programmes in that organ site. We are just beginning to understand what those changes are and how they influence the disease state. Overall, we hope to bring together the varying degrees of fluctuations in the microbiome at the major organ sites and how these changes affect the normal cellular processes because of dysregulation, leading to proliferation of the associated tissues. |
| the eukaryotic cell cycle and cancer: DNA Replication and Human Disease Melvin L. DePamphilis, 2006 At least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trillion meters of DNA! And yet, with only two exceptions, the genome is replicated once and only once each time a cell divides. How is this feat accomplished? What happens when errors occur? This book addresses these questions by presenting a thorough analysis of the molecular events that govern DNA replication in eukaryotic cells. The association between genome replication and cell proliferation, disease pathogenesis, and the development of targeted therapeutics is also addressed. At least 160 proteins are involved in replicating the human genome, and at least 40 diseases are caused by aberrant DNA replication, 35 by mutations in genes required for DNA replication or repair, 7 by mutations generated during mitochondrial DNA replication, and more than 40 by DNA viruses. Consequently, a growing number of therapeutic drugs are targeted to DNA replication proteins. This authoritative volume provides a rich source of information for researchers, physicians, and teachers, and will stimulate thinking about the relevance of DNA replication to human disease. |
| the eukaryotic cell cycle and cancer: The Retinoblastoma Protein Pedro G. Santiago-Cardona, 2018-02-22 This volume covers the mechanisms of pRb inactivation detailing repressive mechanisms commonly associated to cancer, and representative of the experimentally relevant tests used in the establishment of cancer diagnosis and prognosis. Chapters contain protocols and in-depth discussions for commonly used experimental approaches to assess the status and function of components of the pRb pathway, including pRb itself, in cell lines and biological samples.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, The Retinoblastoma Protein aims to serve as a guide to assist molecular cancer biologists in their search for understanding of the molecular functions of this preeminent tumor suppressor. |
| the eukaryotic cell cycle and cancer: Human Genes and Genomes Leon E. Rosenberg, Diane Drobnis Rosenberg, 2012-05-21 In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor's office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and its relevance across disciplines. - Bridges the gap between basic human genetic understanding and one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease - Includes the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more - Explores ethical, legal, regulatory and economic aspects of genomics in medicine - Integrates historical (classical) genetics approach with the latest discoveries in structural and functional genomics |
| the eukaryotic cell cycle and cancer: Cell Cycle Control Eishi Noguchi, Mariana C. Gadaleta, 2016-08-23 A collection of new reviews and protocols from leading experts in cell cycle regulation, Cell Cycle Control: Mechanisms and Protocols, Second Edition presents a comprehensive guide to recent technical and theoretical advancements in the field. Beginning with the overviews of various cell cycle regulations, this title presents the most current protocols and state-of-the-art techniques used to generate latest findings in cell cycle regulation, such as protocols to analyze cell cycle events and molecules. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Cell Cycle Control: Mechanisms and Protocols, Second Edition will be a valuable resource for a wide audience, ranging from the experienced cell cycle researchers looking for new approaches to the junior graduate students giving their first steps in cell cycle research. |
| the eukaryotic cell cycle and cancer: Regulation of the Eukaryotic Cell Cycle Joan Marsh, 2008-04-30 Comprised of the latest developments in cell cycle research, it analyzes the principles underlying the control of cell division. Offers a framework for future investigation, especially that aimed toward understanding and treatment of cancer. |
| the eukaryotic cell cycle and cancer: Understanding Viruses Teri Shors, 2009 Combining the molecular, clinical, and historical aspects of virology, Understanding Viruses is a textbook for the modern undergraduate virology course. The text provides an introduction to human viral diseases. Additional chapters on viral diseases of animals; the history of clinical trials, gene therapy, and xenotransplantation; prions and viroids; plant viruses; and bacteriophages add to the coverage.--Jacket. |
| the eukaryotic cell cycle and cancer: Concepts in Cell Biology Vaidurya Pratap Sahi, F. Baluška, 2018 This book discusses central concepts and theories in cell biology from the ancient past to the 21st century, based on the premise that understanding the works of scientists like Hooke, Hofmeister, Caspary, Strasburger, Sachs, Schleiden, Schwann, Mendel, Nemec, McClintock, etc. in the context of the latest advances in plant cell biology will help provide valuable new insights. Plants have been an object of study since the roots of the Greek, Chinese and Indian cultures. Since the term cell was first coined by Robert Hooke, 350 years ago in Micrographia, the study of plant cell biology has moved ahead at a tremendous pace. The field of cell biology owes its genesis to physics, which through microscopy has been a vital source for piquing scientists' interest in the biology of the cell. Today, with the technical advances we have made in the field of optics, it is even possible to observe life on a nanoscale. From Hooke's observations of cells and his inadvertent discovery of the cell wall, we have since moved forward to engineering plants with modified cell walls. Studies on the chloroplast have also gone from Julius von Sachs' experiments with chloroplast, to using chloroplast engineering to deliver higher crop yields. Similarly, advances in fluorescent microscopy have made it far easier to observe organelles like chloroplast (once studied by Sachs) or actin (observed by Bohumil Nemec). If physics in the form of cell biology has been responsible for one half of this historical development, biochemistry has surely been the other. |
| the eukaryotic cell cycle and cancer: PCAT Prep Book 2020-2021 , 2020-04-17 Test Prep Books' PCAT Prep Book 2020-2021: PCAT Study Guide and Practice Test Questions for the Pharmacy College Admissions Test [2nd Edition] Made by Test Prep Books experts for test takers trying to achieve a great score on the PCAT exam. This comprehensive study guide includes: Quick Overview Find out what's inside this guide! Test-Taking Strategies Learn the best tips to help overcome your exam! Introduction Get a thorough breakdown of what the test is and what's on it! Study Prep Plan Writing Writing the Essay, and Conventions of Standard English Biological Processes Covers General Biology, Microbiology, Health, Anatomy, and Physiology sections. Chemical Processes Covers General Chemistry, Organic Chemistry, and Basic Biochemistry Processes. Quatative Reasoning Covers Basic Math, Algebra, Probablility, Statistics, and Caclulus. Practice Questions Practice makes perfect! Detailed Answer Explanations Figure out where you went wrong and how to improve! Studying can be hard. We get it. That's why we created this guide with these great features and benefits: Comprehensive Review: Each section of the test has a comprehensive review created by Test Prep Books that goes into detail to cover all of the content likely to appear on the test. Practice Test Questions: We want to give you the best practice you can find. That's why the Test Prep Books practice questions are as close as you can get to the actual PCAT test. Answer Explanations: Every single problem is followed by an answer explanation. We know it's frustrating to miss a question and not understand why. The answer explanations will help you learn from your mistakes. That way, you can avoid missing it again in the future. Test-Taking Strategies: A test taker has to understand the material that is being covered and be familiar with the latest test taking strategies. These strategies are necessary to properly use the time provided. They also help test takers complete the test without making any errors. Test Prep Books has provided the top test-taking tips. Customer Service: We love taking care of our test takers. We make sure that you interact with a real human being when you email your comments or concerns. Anyone planning to take this exam should take advantage of this Test Prep Books study guide. Purchase it today to receive access to: PCAT review materials PCAT practice questions Test-taking strategies |
Eukaryote - Wikipedia
Eukaryotes are organisms that range from microscopic single cells, such as picozoans under 3 micrometres across, [6] to animals like the blue whale, weighing up to 190 tonnes and …
Eukaryotic Cell - The Definitive Guide | Biology Dictionary
Nov 6, 2020 · A eukaryotic cell contains membrane-bound organelles such as a nucleus, mitochondria, and an endoplasmic reticulum. Organisms based on the eukaryotic cell include …
Eukaryote | Definition, Structure, & Facts | Britannica
May 14, 2025 · eukaryote, any cell or organism that possesses a clearly defined nucleus. The eukaryotic cell has a nuclear membrane that surrounds the nucleus, in which the well-defined …
Prokaryotes vs Eukaryotes: Key Cell Differences | Osmosis
6 days ago · Eukaryotic cells are cells containing membrane-bound organelles and are the basis for both unicellular and multicellular organisms. In contrast, prokaryotic cells do not have any …
Eukaryotic Cell: Definition, Structure, & Examples - Science Facts
Feb 3, 2023 · Eukaryotic cells are defined as cells that contain an organized nucleus and membrane-bound organelles. They have a more advanced structural organization that is large …
Eukaryotes and prokaryotes - Cell structure - AQA - GCSE …
Eukaryotic cell: DNA in a nucleus - plasmids are found in a few simple eukaryotic organisms: Prokaryotic cell
Eukaryotic Cell Definition - BYJU'S
What is a Eukaryotic Cell? Eukaryotic cells have a nucleus enclosed within the nuclear membrane and form large and complex organisms. Protozoa, fungi, plants, and animals all have …
Eukaryotic Cell: Structure and Function - Biology LibreTexts
By definition, eukaryotic cells are cells that contain a membrane-bound nucleus, a structural feature that is not present in bacterial or archaeal cells. In addition to the nucleus, eukaryotic …
eukaryote / eucariote | Learn Science at Scitable - Nature
Eukaryotes are organisms whose cells contain a nucleus and other membrane-bound organelles. There is a wide range of eukaryotic organisms, including all animals, plants, fungi, and …
Eukaryotic Cell: Definition, structure and organelles - Kenhub
Jul 24, 2023 · The eukaryotic cells types are generally found in animals, plants, algae, and fungi. For the purpose of this article, the primary focus will be the structure and histology of the …
Eukaryote - Definition and Examples - Biology Online Dictionary
Sep 16, 2022 · Eukaryote refers to any of the single-celled or multicellular organisms whose cell contains a distinct, membrane-bound nucleus. Organisms such as animals, plants, fungi, and …
Eukaryotic Cell: Definition, Structure & Function (With Analogy ...
Jun 24, 2019 · What exactly are eukaryotic cells? They're one of two major classifications of cells – eukaryotic and prokaryotic. They're also the more complex of the two. Eukaryotic cells …
Eukaryotic Cell – Diagram, Definition, Facts - Science Notes and …
Feb 11, 2025 · A eukaryotic cell is a cell that contains a nucleus enclosed within a membrane and has other membrane-bound organelles that perform specialized functions. The term eukaryotic …
Eukaryote - Definition and Types - Biology Dictionary
Apr 27, 2017 · Eukaryotes are organisms whose bodies are made up of eukaryotic cells, such as protists, fungi, plants and animals. Eukaryotic cells are cells that contain a nucleus and …
Eukaryotes Explained: Here’s What You Need to Know
Eukaryotes are organisms made up of one or many cells which have a clearly delineated nucleus bound by a nuclear membrane. In fact the name “Eukaryota” is greek and loosely means well …
Eukaryotic Cells - Basic Biology
Mar 9, 2016 · A eukaryotic cell is any cell with a true nucleus and organelles. The nucleus contains the majority of the cell’s DNA and is the genetic hub of a eukaryotic cell. Organelles …
Eukaryotic Cells - Visible Body
Plant and animal cells are eukaryotic, meaning that they have nuclei. Eukaryotic cells are found in plants, animals, fungi, and protists. They generally have a nucleus —an organelle surrounded …
Eukaryotic Cells - GeeksforGeeks
Nov 8, 2023 · Eukaryotic cells include all the protists, plants, animals, and fungi. It forms the domain Eukaryota and possesses an organized nucleus with a nuclear envelope. Their …
Eukaryotic Cells | Learn Science at Scitable - Nature
Eukaryotic cells are more complex than prokaryotic ones because of specialized organelles. Learn how ancient collaborations between cells gave eukaryotes an important energy boost.
Transcription in Eukaryotes vs. Prokaryotes: Initiation, Regulation ...
Jun 7, 2025 · Eukaryotic cells have a complex structure, a fine transcription process, and multi-layer regulation; prokaryotic cells are simple in structure, and transcription pays more attention …
Eukaryotic cells - Khan Academy
Eukaryotic cells - Khan Academy
Eukaryotic Cell - Definition, Characteristics, Structure ... - Examples
Jul 5, 2024 · What is Eukaryotic cell? A eukaryotic cell is a type of cell that is characterized by the presence of a nucleus enclosed within a membrane, distinguishing it fundamentally from …
Prokaryotic vs ( Eukaryotic Cells: Key Concepts and Differences ...
Dec 3, 2024 · Eukaryotic cells are much larger so they have created organelles that have specific jobs to ensure that all processes are carried out. State two characteristics that all living cells …
Origin and Evolution of Genes in Eukaryotes: Mechanisms ... - MDPI
2 days ago · The origin and evolution of genes are central themes in evolutionary biology and genomics, shedding light on how molecular innovations shape biological complexity and …
Organelles in eukaryotic cells (video) | Khan Academy
Organelles in eukaryotic cells (video) | Khan Academy
Eukaryote - Wikipedia
Eukaryotes are organisms that range from microscopic single cells, such as picozoans under 3 micrometres across, [6] to animals like the blue whale, …
Eukaryotic Cell - The Definitive Guide | Biology Dictionary
Nov 6, 2020 · A eukaryotic cell contains membrane-bound organelles such as a nucleus, mitochondria, and an endoplasmic reticulum. Organisms …
Eukaryote | Definition, Structure, & Facts | Britannica
May 14, 2025 · eukaryote, any cell or organism that possesses a clearly defined nucleus. The eukaryotic cell has a nuclear membrane that surrounds …
Prokaryotes vs Eukaryotes: Key Cell Differences | Osmosis
6 days ago · Eukaryotic cells are cells containing membrane-bound organelles and are the basis for both unicellular and multicellular …
Eukaryotic Cell: Definition, Structure, & Examples - Scien…
Feb 3, 2023 · Eukaryotic cells are defined as cells that contain an organized nucleus and membrane-bound organelles. They have a more …
